![]() ![]() Essentially, it can be helpful in keeping the hormones in check and in balance. DIM helps prevent these harmful hormones from getting into their receptors and helps prevent the conversion of testosterone into estrogen. When hormone receptors in individuals are over sensitive, hormones like testosterone can trigger excess production, which causes skin cells to become sticky, leading to breakouts due to clogged pores ( x). AcneĭIM can treat acne because it affects testosterone, which has a connection to acne. While DIM does not directly mimic or replace estrogen, using it will promote an improved estrogen metabolism. These “good” metabolites are also important to overall health because they contain important antioxidant activity that can explain why estrogen in women can slow the progress of some age-related diseases such as arthritis, heart disease and cancer ( x). It is possible that these “good” metabolites help lower the risk of cancer and decrease the symptoms of estrogen over-stimulation, which can include growing uterine fibroid tumors, breast tenderness, cervical problems and endometriosis ( x). DIM helps estrogen break down into the “good” kind. When estrogen breaks down, it can break down into either “good” metabolites or “bad” metabolites. It is too soon to tell whether DIM may significantly fight these forms of cancer because there has been a lack of research conducted. ![]() Unfortunately, a study published in 2012 failed to show any significant benefit on cervical cell changes among the 551 women who participated ( x). Some data suggests that taking DIM supplements may slow the development of cervical cancer. However, it increased in the men who took the placebo ( x). In a separate study that explored the role of DIM in the reversal of high-grade prostatic intraepithelial neoplasia (PIN), it was found that the structural changes in the prostate among those men who took DIM declined. The study found that adding DIM to the treatment plan may in fact lead to a better outcome ( x). In 2016, a study was conducted that looked into the positive effects of using DIM alongside the use of enzalutamide in men with castration-resistant prostate cancer. That’s why DIM is believed to help protect prostate tissue from the possible development of prostate cancer. When estrogen levels are unbalanced in men, their health can take a serious hit. In fact, it is sometimes taken by men to help manage enlarged prostates. DIM can positively influence estrogen metabolism and balance out hormone levels. Research also shows that DIM contains strong anticancer properties ( x). However, these are preliminary findings and more research is necessary in order to back these findings. There have been preliminary studies indicating that DIM may help protect against prostate, ovarian and colon cancer as well. ![]() In the few clinical studies that have been conducted, it has been suggested that DIM may help prevent the growth of cancer cells - specifically breast cancer cells. Diindolylmethane Benefits May Help Prevent Cancer DIM is the most studied of all 13C metabolites and is being studied as a chemo-protective compound for certain types of cancer ( x). This ultimately helps improve the process of breaking down estrogen ( x). Metabolites are famously useful for supporting the liver detoxification process. Each of these vegetables belong to the Brassica family ( x). But did you know that diindolylmethane (also known as DIM) is one of the reasons the Brassica family of vegetables is considered so healthy ( x)? DIM is a metabolite of indole-3-carbinol (13C), which is a compound present in cruciferous vegetables such as broccoli, cauliflower and cabbage. We all know that vegetables are good for us and for our overall health. ![]()
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